# TabLab-Hub

> Drug-discovery tools that run entirely in your browser tab: nothing is uploaded, no account, free to use. Each tool is an ordinary web page that anyone, or any agent with a browser, can open and use.

## Tools

- [Mol3D](https://mol3d.com/): What does this molecule look like in 2D and in 3D? Type, paste, draw or open a molecule. Mol3D shows it in 2D, builds its 3D structure with a force field, and lets you turn bonds and move atoms by hand, with the energy. Everything stays in your tab. Input: SMILES, file or drawing. Output: 2D and 3D views. Sends: The anonymous count of visits (opened, run, downloaded) to its own address. A molecule or a file is never uploaded.
  - Open on an input (a link; the part after # is not sent to our server): https://mol3d.com/#smiles=<percent-encoded SMILES: 1 to 200 printable characters, no space; hash only>, or https://mol3d.com/#random for a molecule drawn at random from its own lists
- [Pocket2D](https://pocket2d.com/): Which residues does this ligand touch, and how? Open a structure or type a PDB code. Pocket2D draws the ligand in clean 2D with the binding-site residues around it, and types and measures every contact: hydrogen bonds, salt bridges, pi-stacking, cation-pi, halogen bonds, metal coordination, hydrophobic contacts. A 3D view sits beside it. Input: File, or PDB code from RCSB. Output: 2D diagram (SVG), 3D view. Sends: The anonymous count of visits (opened, run, downloaded) to its own address. The PDB code you type, or the Random button picks, goes to files.rcsb.org, which returns the structure.
  - Open on an input (a link; the part after # is not sent to our server): https://pocket2d.com/#pdb=<a 4-character PDB code, a digit first; add &ligand=... to choose the ligand>, or https://pocket2d.com/#random for an entry drawn at random from its own list
  - Example: [Try 1IEP](https://pocket2d.com/#pdb=1IEP)
- [Target-ID](https://targetidentifier.com/): Which proteins is this molecule likely to bind? Type, paste or draw a molecule. Target-ID ranks proteins by comparing it with the known ligands of ChEMBL, BindingDB, the PDB and PubChem, and shows the ligands behind every rank so you can judge it by eye. It also looks up 52 safety anti-targets and recognises known natural products. Input: SMILES or drawing. Output: Ranked targets, ligands. Sends: After loading, only the anonymous count of visits (opened, run) to its own address. A PDB code opens Pocket2D only when you click it.
  - Open on an input (a link; the part after # is not sent to our server): https://targetidentifier.com/#smiles=<percent-encoded SMILES: 1 to 200 printable characters, no space; hash only>, or https://targetidentifier.com/#random for a molecule drawn at random from its database
- [LinkerBuilder 3D](https://linkerbuilder3d.com/): Can a chemical linker span these two atoms? Load one structure with a ligand bound in each of two receptors and pick an anchor atom on each. LinkerBuilder maps the clash-free routes between them, folds a linker onto them (yours, or combinations of PEG, alkyl and click-chemistry pieces), and answers No, Maybe or Yes with the numbers behind it. Input: Structure with two ligands. Output: Routes, verdict, 3D placements. Sends: Only the anonymous count of visits (opened, run) to its own address, never a structure.

## Questions

**Is anything uploaded?** No. Molecules and structures stay in your browser tab. Each tool counts visits anonymously. Pocket2D sends a PDB code to RCSB when it fetches an entry, including from a link that names one or draws one.

**How do I open a tool on a molecule or a structure?** Use a card's Random button, or link to a tool with the address forms in llms.txt: Mol3D and Target-ID accept #smiles= or #random, Pocket2D #pdb=CODE or #random. What follows the # is not sent to the tool's own server.

**How do I cite them?** Cite the web address of the page you used.

## Notes

- Home: https://tablabhub.com/
- Everything is computed in the visitor's browser tab. Molecules and structure files are not sent anywhere; Pocket2D sends only a PDB code to RCSB when it fetches an entry by code.
- Some tools download large public databases on the first visit; each tool's note says how large.
- Machine-readable index of the tools above: /tools.json
- Free for research or business. The databases inside the tools keep their own licences; the home page lists them under Credits.